By Pierfausto Seneci
This publication is a neurochemistry-based spouse for Protein Misfolding and Neurodegenerative illnesses: Molecular Targets, an Elsevier identify through an identical writer publishing in December 2014. whereas the 1st ebook specializes in biology and molecular ambitions, this better half publication describes how those ambitions are regulated by means of small molecules and disease-modifying compounds. The publication starts off with a short creation to how key proteins turn into dysfunctional, and every next bankruptcy describes significant disorder mechanisms in Alzheimer’s and different tauopathies. homes and improvement prestige of those molecular goals and illness mechanisms are completely defined, as are small molecule effectors of autophagy and dis-aggregating brokers.
• Written to supply accomplished insurance of neurodegenerative disease-modifying compounds;
• offers discipline-specific chapters that conceal medicinal chemistry and scientific applications;
• offers an outline of greater than 2 hundred chemical sessions and lead compounds, performing on chosen molecular objectives which are of relevance to any neurodegenerative disorder;
• insurance of misfolding ailments, chaperone proteins, ubiquitination and autophagy/oncology makes this ebook compatible for structural neurochemists, chemists, biologists, non-CNS scientists, and scientists drawn to drug discovery.
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Additional resources for Chemical Modulators of Protein Misfolding and Neurodegenerative Disease
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