By Ismithers, Smithers Rapra
Endocrine Disruptors 2011 is a day symposium organised by way of iSmithers, and sister businesses Springborn Smithers and Smithers Viscient, geared toward addressing key themes concerning the evaluate of inauspicious results at the endocrine method and corresponding regulatory standards. The convention will compile specialists from academia, executive, and from around the world to target present and destiny developments in checking out, interpretation and evaluate of try out effects and the way this pertains to or impacts regulatory actions.
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Extra info for Endocrine Disruptors 2011
G. VTG-depression in females) may be caused by systemic toxicity, or by genuine responses to endocrine active substances, counteracted by systemic effects. g. g. sex-ratio in FSDT). This may indicate that the biomarker is more sensitive, but it could also just imply that the test was too short to record an effect on the apical endpoint. Such conflicts will provide useful information when deciding if more advanced testing is desirable. : • Have the same endpoints been addressed in an equally sensitive way?
9 Under Regulation 1107/2009, an active substance shall only be approved if it is not considered to have endocrine disrupting properties, unless the exposure to humans is negligible. ”10 Thus, the burden of proof will be on the operator to prove that the exposure to humans is negligible. As far as criteria for endocrine disruption are concerned the EU is yet to adopt specific harmonised criteria, However, by 14 December 2013, the Commission is required to present a draft of the measures concerning specific scientific criteria for the determination of endocrine disrupting properties.
In fact, many of the category 1 chemicals on the list are already subject to bans or restrictions or are being addressed under existing EU legislation, although for reasons not necessarily related to endocrine disruption. htm Page 3 of 12 pages Paper 5 8-9 February 2011-Zurich, Switzerland Endocrine Disruptors 2011 A database on the DG Environment website currently holds a compilation of this information, although the EU’s Joint Research Centre (“JRC”) will soon take over ownership, relaunching it as a web-based information platform on endocrine active substances that will be available for consultation, in particular by the international scientific community.